FBXW5

BT-AP10013

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human FBXW5

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.132% sodium azide.

-20°C for 1 year

This gene encodes a member of the F-box protein family| members of which are characterized by an approximately 40 amino acid motif| the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box)| which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains| Fbls containing leucine-rich repeats| and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains| in addition to an F-box motif| so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene| however| they were found to be nonsense-mediated mRNA decay (NMD) candidates| hence not represented.

Human: Q969U6; Mouse: Q9QXW2; Rat: Q4KLI9;

Human: 54461; Mouse: 30839; Rat: 362081

FBXW5; F-box/WD repeat-containing protein 5; F-box and WD-40 domain-containing protein 5)

Epigenetics and nuclear signaling

FBXW5