FILA2

BT-AP10040

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human FILA2

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

The filaggrin-like protein encoded by this gene is upregulated by calcium| proteolyzed by calpain 1| and is involved in epithelial homeostasis. The encoded protein is required for proper cornification in skin| with defects in this gene being associated with skin diseases. This protein also has a function in skin barrier protection. In fact| in addition to providing a physical barrier| C-terminal fragments of this protein display antimicrobial activity against P. aeruginosa.

Human: Q5D862; Mouse: Q2VIS4;

263010

Human: 388698; Mouse: 229574

FILA2

Signal transduction

FLG2