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Home > Product > Antibody > GEN Rabbit Polyclonal Antibody

GEN Rabbit Polyclonal Antibody

GEN Rabbit Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse

Applications: WB

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB

Product overview

Full product name

GEN

Code

BT-AP10142

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

Synthesized peptide derived from human GEN

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family| whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains. The protein encoded by this gene is involved in resolution of Holliday junctions| which are intermediate four-way structures that covalently link DNA during homologous recombination and double-strand break repair. The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that can be ligated. In addition| this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity. Alternative splicing results in multiple transcript variants.

Uniprot accession

Molecular weight

99880

Gene ID

Human: 348654; Mouse: 209334

Synonyms

GEN

Research area

Epigenetics and nuclear signaling

Target protein

GEN1

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000

Images

Western blot analysis of lysates from Jarkat cells, primary antibody was diluted at 1:1000, 4°C overnight

Protocols

References

Customer reviews and Q&As

No reviews
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Product size

Price

  • 100ul

    $275.00

  • 50ul

    $180.00

  • 20ul

    $108.00

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Lead time: Within one week

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