LIN28A

BT-AP11043

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized phosho peptide around human LIN28A (Ser200)

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues.

Human: Q9H9Z2; Mouse: Q8K3Y3;

Human: 79727; Mouse: 83557

LIN28A ;Ser200 ; Protein lin-28 homolog A; Lin-28A; Zinc finger CCHC domain-containing protein 1

Epigenetics and nuclear signaling; Developmental biology; Neuroscience; Stem cells

LIN28A