MKK7

BT-AP03618

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized phosho peptide around human MKK7 (Ser271 and Thr275)

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2| and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1| MAP3K2/MEKK2|MAP3K3/MEKK5| and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines| and environmental stresses. Alternative splicing results in multiple transcript variants.

Human: O14733; Mouse: Q8CE90; Rat: Q4KSH7;

Human: 5609; Mouse: 26400; Rat: 363855

MKK7 ;Ser271/Thr275; Dual specificity mitogen-activated protein kinase kinase 7; MAP kinase kinase 7; MAPKK 7; EC 2.7.12.2; JNK-activating kinase 2; MAPK/ERK kinase 7; MEK 7; Stress-activated protein kinase kinase 4; SAPK kinase 4; SAPKK-4; SAPKK4; c-Jun N-terminal kinase kinase 2; JNK kinase 2; JNKK 2

Immunology; Metabolism; Signal transduction

MAP2K7