NLTP

BT-AP03830

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human NLTP

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2)| as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein| and the transcript initiated from the distal promoter encodes the shorter SCP2 protein| with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids| while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism| and may play a role in Zellweger syndrome| in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants| some encoding different isoforms.

Human: P22307; Mouse: P32020; Rat: P11915;

60170

Human: 6342; Mouse: 20280; Rat: 25541

NLTP

Cancer; Metabolism; Signal transduction

SCP2