PACRG

BT-AP11766

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human PACRG

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a protein that is conserved across metazoans. In vertebrates| this gene is linked in a head-to-head arrangement with the adjacent parkin gene| which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones| including heat shock proteins 70 and 90| and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients| and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene.

Human: Q96M98; Mouse: Q9DAK2;

32560

Human: 135138; Mouse: 69310

PACRG

Cell biology; Neuroscience

PACRG