PRDM2

BT-AP12183

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human PRDM2

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein| estrogen receptor| and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized| it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma| (2) act as a transcriptional activator of the heme-oxygenase-1 gene| and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.

Human: Q13029; Rat: Q63755;

188980

Human: 7799; Rat: 313678

PRDM2

Cancer; Epigenetics and nuclear signaling

PRDM2