PSB11

BT-AP12200

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human PSB11

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

Proteasomes generate peptides that are presented by major histocompatibility complex (MHC) I molecules to other cells of the immune system. Proteolysis is conducted by 20S proteasomes| complexes of 28 subunits arranged as a cylinder in 4 heteroheptameric rings: alpha-1 to -7| beta-1 to -7| beta-1 to -7| and alpha-1 to -7. The catalytic subunits are beta-1 (PSMB6; MIM 600307)| beta-2 (PSMB7; MIM 604030)| and beta-5 (PSMB5; MIM 600306). Three additional subunits| beta-1i (PSMB9; MIM 177045)| beta-2i (PSMB10; MIM 176847)| and beta-5i (PSMB8; MIM 177046)| are induced by gamma-interferon (IFNG; MIM 147570) and are preferentially incorporated into proteasomes to make immunoproteasomes. PSMB11| or beta-5t| is a catalytic subunit expressed exclusively in cortical thymic epithelial cells (Murata et al.| 2007

Human: A5LHX3; Mouse: Q8BG41;

33000

Human: 122706; Mouse: 73902

PSB11

Cell biology; Immunology

PSMB11