SELH

BT-AP04690

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human SELH

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a nucleolar protein| which belongs to the SelWTH family. It functions as an oxidoreductase| and has been shown to protect neurons against UVB-induced damage by inhibiting apoptotic cell death pathways| promote mitochondrial biogenesis and mitochondrial function| and suppress cellular senescence through genome maintenance and redox regulation. This protein is a selenoprotein| containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon| which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure| designated the Sec insertion sequence (SECIS) element| that is necessary for the recognition of UGA as a Sec codon| rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene.

Human: Q8IZQ5; Mouse: Q3UQA7;

13420

Human: 280636; Mouse: 72657

SELH

Epigenetics and nuclear signaling

SELH