TCPR2

BT-AP05059

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human TCPR2

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

The protein encoded by this gene is a member of the tectonin beta-propeller repeat-containing (TECPR) family| and contains both TECPR and tryptophan-aspartic acid repeat (WD repeat) domains. This gene has been implicated in autophagy| as reduced expression levels of this gene have been associated with impaired autophagy. Recessive mutations in this gene have been associated with a hereditary form of spastic paraparesis (HSP). HSP is characterized by progressive spasticity and paralysis of the legs. There is also some evidence linking mutations in this gene with birdshot chorioretinopathy (BSCR)| which results in inflammation of the choroid and retina. Alternative splicing results in multiple transcript variants encoding different isoforms.

Human: O15040;

155210

Human: 9895

TCPR2

Cell biology

TECPR2