Aldo-keto reductase family 1 member C4

BT-AP06132

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human protein . at AA range: 1-80

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Human: P17516;

Human: 1109

Aldo-keto reductase family 1 member C4 ;EC 1.1.1.-;3-alpha-HSD1;3-alpha-hydroxysteroid dehydrogenase type I;EC 1.1.1.50;Chlordecone reductase;CDR;EC 1.1.1.225;Dihydrodiol dehydrogenase 4

Cancer; Metabolism; Signal transduction

AKR1C4