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Home > Product > Antibody > CKR-5 Polyclonal Antibody

CKR-5 Polyclonal Antibody

CKR-5 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Rat, Mouse

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

C-C chemokine receptor type 5

Code

BT-AP14980

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

Synthetic peptide from human protein at AA range: 151-200

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemok

Uniprot accession

Gene ID

Human: 1234; Mouse: 12774

Synonyms

C-C chemokine receptor type 5 ;C-C CKR-5;CC-CKR-5;CCR-5;CCR5;CHEMR13;HIV-1 fusion coreceptor;CD antigen CD195; C-C chemokine receptor type 5; C-C CKR-5; CC-CKR-5; CCR-5; CCR5; CHEMR13; HIV-1 fusion coreceptor; CD antigen CD195

Research area

Neuroscience; Immunology; Microbiology; Signal transduction; Cancer; Cardiovascular

Target protein

CCR5

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
IHC-p 1: 500 - 1: 200
ELISA 1: 20000
ELISA 1: 10000 - 1: 20000

Images

Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:200
Western blot analysis of 293T lysate, antibody was diluted at 2000. Secondary antibody was diluted at 1:20000

Protocols

References

Customer reviews and Q&As

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

Add to Cart

Lead time: Within one week

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