Full product name
Tumor necrosis factor receptor superfamily member EDAR
Code
BT-AP15365
Host
Rabbit
Isotype
IgG
Size
100ul,50ul,20ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human protein . at AA range: 50-130
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.
Uniprot accession
Gene ID
Human: 10913
Synonyms
Tumor necrosis factor receptor superfamily member EDAR ;Anhidrotic ectodysplasin receptor 1;Downless homolog;EDA-A1 receptor;Ectodermal dysplasia receptor;Ectodysplasin-A receptor
Research area
Epigenetics and nuclear signaling; Signal transduction
Target protein
EDAR
