Full product name
Fumarate hydratase, mitochondrial
Code
BT-AP09147
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
Recombinant Protein of Fumarate hydratase, mitochondrial
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Storage
-20°C for 1 year
Background
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.
Uniprot accession
Gene ID
Human: 2271; Mouse: 14194
Synonyms
Fumarate hydratase, mitochondrial; Fumarate hydratase, mitochondrial; Fumarase; EC 4.2.1.2
Research area
Immunology
Target protein
FH
