Gamma-aminobutyric acid receptor subunit alpha-4

BT-AP15686

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthetic Peptide of GABA A Receptor α4

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.

Human: P48169; Mouse: Q9D6F4; Rat: P28471;

Human: 2557

Gamma-aminobutyric acid receptor subunit alpha-4 ;GABA;A receptor subunit alpha-4; GABRA4; Gamma-aminobutyric acid receptor subunit alpha-4; GABA;A receptor subunit alpha-4

Neuroscience

GABRA4