Full product name
Lysine-specific demethylase 5A
Code
BT-AP10664
Host
Rabbit
Isotype
IgG
Size
100ul,50ul,20ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human protein . at AA range: 720-800
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression.
Uniprot accession
Gene ID
Human: 5927
Synonyms
Lysine-specific demethylase 5A ;EC 1.14.11.-;Histone demethylase JARID1A;Jumonji/ARID domain-containing protein 1A;Retinoblastoma-binding protein 2;RBBP-2
Research area
Epigenetics and nuclear signaling
Target protein
KDM5A