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Home > Product > Antibody > Na+/K+-ATPase alpha 1 Polyclonal Antibody

Na+/K+-ATPase alpha 1 Polyclonal Antibody

Na+/K+-ATPase alpha 1 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Rat

Applications: WB, IF, ICC, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Rat

Applications: WB, IF, ICC, ELISA

Product overview

Full product name

Sodium/potassium-transporting ATPase subunit alpha-1

Code

BT-AP11683

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from rat ATP1 alpha1/Na+K+ ATPase1. AA range:15-64

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

The ATPase Na+/K+ transporting subunit alpha 1 encoded by ATP1A1 belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.

Uniprot accession

Molecular weight

113054

Gene ID

Rat: 24211

Synonyms

Sodium/potassium-transporting ATPase subunit alpha-1; ATP1A1; Sodium/potassium-transporting ATPase subunit alpha-1; Na;+/K;+ ATPase alpha-1 subunit; Sodium pump subunit alpha-1

Research area

Cancer; Metabolism ; Neuroscience; Signal transduction; Tags & cell markers

Target protein

ATP1A1

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
IF 1: 200 - 1: 1000
ICC 1: 200 - 1: 1000
ELISA 1: 40000

Images

Immunofluorescence analysis of HeLa cells, using ATP1 alpha1/Na+K+ ATPase1 Antibody. The picture on the right is blocked with the synthesized peptide.
Western Blot analysis of HeLa cells using Na+/K+-ATPase α1 Polyclonal Antibody
Western blot analysis of lysates from HeLa cells, using ATP1 alpha1/Na+K+ ATPase1 Antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of the lysates from RAW264.7cells using ATP1α1/Na+K+ ATPase1 antibody.

Protocols

References

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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