PARP-1

BT-AP12792

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized Acetyl peptide derived from human PARP-1. at AA range: K521

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Human: P09874; Mouse: P11103;

Human: 142

PARP-1 ; Poly [ADP-ribose; polymerase 1; PARP-1; EC 2.4.2.30; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD;+ ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose; synthase 1

Epigenetics and nuclear signaling; Signal transduction

PARP1