Full product name
Serine/threonine-protein phosphatase 2A activator
Code
BT-AP13392
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from part region of human protein
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
Uniprot accession
Gene ID
Human: 5524
Synonyms
Serine/threonine-protein phosphatase 2A activator ;EC 5.2.1.8;PP2A, subunit B', PR53 isoform;Phosphotyrosyl phosphatase activator;PTPA;Serine/threonine-protein phosphatase 2A regulatory subuni
Research area
Signal transduction
Target protein
PPP2R4
