NAD-dependent protein deacetylase sirtuin-4

BT-AP14232

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human protein . at AA range: 30-110

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

Human: Q9Y6E7; Mouse: Q8R216;

Human: 23409

NAD-dependent protein deacetylase sirtuin-4 ;EC 3.5.1.-;NAD-dependent ADP-ribosyltransferase sirtuin-4;EC 2.4.2.-;Regulatory protein SIR2 homolog 4;SIR2-like protein 4

Cardiovascular; Cell biology; Epigenetics and nuclear signaling; Metabolism; Signal transduction

SIRT4