Full product name
Ubiquitin-conjugating enzyme E2 E3
Code
BT-AP15281
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from part region of human protein
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Uniprot accession
Gene ID
Human: 10477
Synonyms
Ubiquitin-conjugating enzyme E2 E3 ;EC 6.3.2.19;UbcH9;Ubiquitin carrier protein E3;Ubiquitin-conjugating enzyme E2-23 kDa;Ubiquitin-protein ligase E3
Research area
Epigenetics and nuclear signaling; Cell biology
Target protein
UBE2E3
