Ubiquitin-conjugating enzyme E2 A/Ubiquitin-conjugating enzyme E2 B

BT-AP15296

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from the C-terminal region of human UBE2A/B.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants.

Human: P49459/P63146; Rat: P63149;

Human: 7320; Rat: 81816

Ubiquitin-conjugating enzyme E2 A/Ubiquitin-conjugating enzyme E2 B; UBE2A; RAD6A; Ubiquitin-conjugating enzyme E2 A; RAD6 homolog A; HR6A; hHR6A; Ubiquitin carrier protein A; Ubiquitin-protein ligase A; UBE2B; RAD6B; Ubiquitin-conjugating enzyme E2 B; RAD6 homolog B; HR6B; hHR6B; Ubiquitin carrier protein B; Ubiquitin-conjugating enzyme E2-17 kDa; Ubiquitin-protein ligase B

Epigenetics and nuclear signaling; Cell biology; Metabolism; Cancer

UBE2A