Full product name
Ubiquitin-conjugating enzyme E2 K
Code
BT-AP15300
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from part region of human protein
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.
Uniprot accession
Gene ID
Human: 3093
Synonyms
Ubiquitin-conjugating enzyme E2 K ;EC 6.3.2.19;Huntingtin-interacting protein 2;HIP-2;Ubiquitin carrier protein;Ubiquitin-conjugating enzyme E2-25 kDa;Ubiquitin-conjugating enzyme E2;25K;
Research area
Epigenetics and nuclear signaling; Cell biology; Neuroscience
Target protein
UBE2K
