Full product name
Ubiquitin carboxyl-terminal hydrolase 14
Code
BT-AP15317
Host
Rabbit
Isotype
IgG
Size
100ul,50ul,20ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from part region of human protein
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Uniprot accession
Gene ID
Human: 9097
Synonyms
Ubiquitin carboxyl-terminal hydrolase 14 ;EC 3.4.19.12;Deubiquitinating enzyme 14;Ubiquitin thioesterase 14;Ubiquitin-specific-processing protease 14
Research area
Cell biology; Epigenetics and nuclear signaling
Target protein
USP14
