Code
BT-MCA2023
Host
Mouse
Isotype
Mouse IgG1
Size
100μL,50μL
Clonality
Monoclonal
Immunogen
Purified recombinant fragment of human PPARGC1B (AA: 195-414) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.
Uniprot accession
Molecular weight
113.2kDa
Gene ID
133522
Synonyms
PERC;ERRL1;PGC1B;PGC-1(beta)
Research area
Cardiovascular,Epigenetics and nuclear signaling,Metabolism,Signal transduction
Target protein
PPARGC1B
