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Home > Product > Antibody > BMAL1 (Acetyl Lys538) Polyclonal Antibody

BMAL1 (Acetyl Lys538) Polyclonal Antibody

BMAL1 (Acetyl Lys538) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ELISA

Product overview

Full product name

BMAL1 (Acetyl Lys538) Antibody

Code

BT-AP00913

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized Acetyl-peptide derived from human BMAL1 around the Acetylation site of Lys538. AA range:501-550

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

The protein encoded by ARNTL is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in ARNTL have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for ARNTL.

Uniprot accession

Molecular weight

68762

Gene ID

Human: 406; Mouse: 11865; Rat: 29657

Synonyms

ARNTL; BHLHE5; BMAL1; MOP3; PASD3; Aryl hydrocarbon receptor nuclear translocator-like protein 1; Basic-helix-loop-helix-PAS protein MOP3Brain and muscle ARNT-like 1; Class E basic helix-loop-helix pr

Research area

Cardiovascular

Target protein

ARNTL

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
ELISA 1: 20000

Images

Western Blot analysis of 293 cells using Acetyl-BMAL1 (K538) Polyclonal Antibody. Secondary antibody was diluted at 1:20000
Western blot analysis of lysate from 293 cells, using BMAL1 (Acetyl-Lys538) Antibody.

Protocols

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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