BRMS-1 Antibody

BT-AP00979

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

The antiserum was produced against synthesized peptide derived from the C-terminal region of human BRMS1. AA range:197-246

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

BRMS1 reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. Breast cancer metastasis-suppressor 1 encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.

Human: Q9HCU9; Mouse: Q99N20; Rat: Q5M7T3;

28461

Human: 25855; Mouse: 107392; Rat: 100911841

BRMS1; Breast cancer metastasis-suppressor 1

Epigenetics and Nuclear Signaling

BRMS1