C/EBP zeta Antibody

BT-AP01023

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

The antiserum was produced against synthesized peptide derived from human CEBPZ. AA range:1-50

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

CEBPZ belongs to the CEBP family. The encoded protein (CCAAT/enhancer binding protein zeta) plays a role in cellular response to environmental stimuli through a transcriptional process that involves heat shock factors, conserved DNA elements (heat shock elements or HSEs) and CCAAT boxes. The protein acts as a DNA-binding transcriptional activator and regulates the heat-shock protein 70 (HSP70) promoter in a CCAAT-dependent manner. The protein is also involved in cell growth and differentiation, particularly, hematopoietic differentiation. Methylation of the promoter of CEBPZ or mutations within CEBPZ may be correlated with occurance of acute myeloid leukemia (AML).

Human: Q03701; Mouse: P53569;

120988

Human: 10153

CEBPZ; CBF2; CCAAT/enhancer-binding protein zeta; CCAAT-box-binding transcription factor; CBF; CCAAT-binding factor

Epigenetics and Nuclear Signaling

CEBPZ