Caspase-6 Antibody

BT-AP01206

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from Caspase-6 . at AA range: 20-100

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

CASP6 (caspase 6) encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of CASP6 results in multiple transcript variants that encode different isoforms.

Human: P55212; Mouse: O08738; Rat: O35397;

33310

Human: 839; Mouse: 12368

CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2

Neuroscience

CASP6