Full product name
CGI-43 Antibody
Code
BT-AP01735
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human CG028. AA range:411-460
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage
-20°C for one year
Background
CCZ1, also known as CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae), CCZ1A, CCZ1B or CGI-43, is a 482 amino acid protein that localizes to the lysosomal membrane and belongs to the CCZ1 family. CCZ1 is encoded by a gene that maps to human chromosome 7, which houses over 1000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.
Uniprot accession
Molecular weight
55866
Gene ID
Human: 221960; Mouse: 231874
Synonyms
CCZ1; C7orf28A; CGI-43; Vacuolar fusion protein CCZ1 homolog; CCZ1B; C7orf28B; Vacuolar fusion protein CCZ1 homolog B; Vacuolar fusion protein CCZ1 homolog-like
Research area
Others
Target protein
CCZ1
