CNOT7 Antibody

BT-AP02037

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

The antiserum was produced against synthesized peptide derived from human CNOT7. AA range:10-59

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

CCR4-NOT transcription complex subunit 7 encoded by CNOT7 binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of CNOT7 results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.

Human: Q9UIV1; Mouse: Q60809;

32745

Human: 29883; Mouse: 18983

CNOT7; CAF1; CCR4-NOT transcription complex subunit 7; BTG1-binding factor 1; CCR4-associated factor 1; CAF-1

Epigenetics and Nuclear Signaling

CNOT7