Dynein IC1 Antibody

BT-AP02767

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

The antiserum was produced against synthesized peptide derived from human DNAI1. AA range:211-260

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

DNAI1 encodes a member of the dynein intermediate chain family. The dynein axonemal intermediate chain 1 is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome. Alternative splicing results in multiple transcript variants.

Human: Q9UI46; Mouse: Q8C0M8; Rat: Q5XIL8;

79283

Human: 27019; Mouse: 68922; Rat: 500442

DNAI1; Dynein intermediate chain 1; axonemal; Axonemal dynein intermediate chain 1

Neuroscience

DNAI1