EAR2 Antibody

BT-AP02803

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

The antiserum was produced against synthesized peptide derived from human NR2F6. AA range:11-60

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

NR2F6, also known as Nuclear receptor subfamily 2 group F member 6, is a nuclear protein belonging to the nuclear hormone receptor family and NR2 subfamily with a nuclear receptor DNA-binding domain. NR2F6 is a nuclear receptor involved in action regulation of the transcription of the GNRH1 gene. It binds to the TGACCT repeat motif enhancing the renin gene and thus acting as a negative modulator of renin gene transcription. NR2F6 is required early in the development of the locus ceruleus (LC), thus in some way contributing to the regulation of the forebrain clock, at least in part, through targeted release of noradrenalin into the cortical area.

Human: P10588; Mouse: P43136; Rat: O09017;

42979

Human: 2063; Mouse: 13864; Rat: 245980

NR2F6; EAR2; ERBAL2; Nuclear receptor subfamily 2 group F member 6; V-erbA-related protein 2; EAR-2

Epigenetics and Nuclear Signaling

NR2F6