FEV Antibody

BT-AP03198

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from the N-terminal region of human FEV.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

FEV (FEV, ETS transcription factor) belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. FEV is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, FEV is fused to the Ewing sarcoma (EWS) gene following chromosome translocations.

Human: Q99581; Mouse: Q8QZW2;

25030

Human: 54738

FEV; PET1; Protein FEV; Fifth Ewing variant protein; PC12 ETS domain-containing transcription factor 1; PC12 ETS factor 1; Pet-1

Neuroscience

FEV