IL-22 Antibody

BT-AP04478

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

The antiserum was produced against synthesized peptide derived from the C-terminal region of human IL22. AA range:121-170

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

IL-10-related T cell-derived inducible factor (IL-22, also known as IL-TIF) is a cytokine that was originally identified in mouse as an IL-9 inducible gene in T cells and mast cells and shows 22% amino acid identity with IL-10. Additionally, IL-22 is induced by IL-9 in thymic lymphomas and by lectins in freshly isolated splenocytes. IL-22 is found in both the thymus and brain, which suggests that the role of this factor is not restricted to the immune system. IL-22 is a ligand for CRF2-4, a member of the class II cytokine receptor family. In contrast to IL-10, IL-22 does not inhibit the production of proinflammatory cytokines by monocytes in response to lipopolysaccharide nor does it impact IL-10 function on monocytes, but it has modest inhibitory effects on IL-4 production from Th2 T cells.

Human: Q9GZX6; Mouse: Q9JJY9;

20011

Human: 50616; Mouse: 50929

IL22; ILTIF; ZCYTO18; Interleukin-22; IL-22; Cytokine Zcyto18; IL-10-related T-cell-derived-inducible factor; IL-TIF

Immunology

IL22