KCNT1 Antibody

BT-AP04777

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

The antiserum was produced against synthesized peptide derived from human KCNT1. AA range:1019-1068

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. KCNT1 (potassium sodium-activated channel subfamily T member 1) encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in KCNT1 cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants.

Human: Q5JUK3; Mouse: Q6ZPR4; Rat: Q9Z258;

138343

Human: 57582; Mouse: 227632; Rat: 60444

KCNT1; KIAA1422; Potassium channel subfamily T member 1; KCa4.1

Neuroscience

KCNT1