NF-E4 (Acetyl Lys43) Antibody

BT-AP05959

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized acetyl-peptide derived from the human NF-E4 around the acetylation site of K43.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

The erythroid-specific protein encoded by NFE4, and the ubiquitous transcription factor CP2, form the stage selector protein(SSP) complex, which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells. Alternate use of an in-frame upstream non-AUG(CUG) translation initiation codon, and a downstream AUG codon, results in two isoforms. While the long isoform(22 kDa) acts as an activator, the short isoform(14 kDa) has been shown to repress gamma-globin gene expression. NFE4 is located in an intron of the FBXL13 gene on the opposite strand.

Human: Q86UQ8;

19019

Human: 58160

NFE4; Transcription factor NF-E4

Others

NFE4