P2X3 Antibody

BT-AP06766

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

The antiserum was produced against synthesized peptide derived from the Internal region of human P2RX3. AA range:81-130

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

The product of P2RX3 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.

Human: P56373; Mouse: Q3UR32; Rat: P49654;

44230

Human: 5024; Mouse: 228139; Rat: 81739

P2RX3; P2X purinoceptor 3; P2X3; ATP receptor; Purinergic receptor

Neuroscience

P2RX3