TGF Beta RI Polyclonal Antibody

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Home > Product > Antibody > TGF Beta RI Polyclonal Antibody

TGF Beta RI Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IF, ELISA

Product overview

Full product name

TGFbeta RI Antibody

Code

BT-AP08970

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human TGF beta Receptor I. AA range:131-180

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

TGF-beta receptor type-1 encoded by TGFBR1 forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The TGF-beta receptor type-1 is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.

Uniprot accession

Human: P36897; Mouse: Q64729; Rat: P80204;

Molecular weight

55960

Gene ID

Human: 7046; Mouse: 21812

Synonyms

TGFBR1; ALK5; SKR4; TGF-beta receptor type-1; TGFR-1; Activin A receptor type II-like protein kinase of 53kD; Activin receptor-like kinase 5; ALK-5; ALK5; Serine/threonine-protein kinase receptor R4;

Research area

Cardiovascular

Target protein

TGFBR1

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IF	1: 200 - 1: 1000
ELISA	1: 10000

Images

Western Blot analysis of COLO205 cells using TGFβ RI Polyclonal Antibody diluted at 1:500

Immunofluorescence analysis of HeLa cells, using TGF beta Receptor I Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from HepG2 and COLO cells, using TGF beta Receptor I Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using TGFβ RI Polyclonal Antibody diluted at 1:500

Western blot analysis of the lysates from HeLa cells using TGF β Receptor I antibody.

Protocols

> Protocol Booklet

References

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

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Lead time: Within one week

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