TIN2 Antibody

BT-AP09039

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

The antiserum was produced against synthesized peptide derived from human TINF2. AA range:71-120

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

TINF2 encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The TERF1 interacting nuclear factor 2 encoded by TINF2 is a critical part of shelterin; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome.

Human: Q9BSI4; Mouse: Q9QXG9;

50023

Human: 26277

TINF2; TIN2; TERF1-interacting nuclear factor 2; TRF1-interacting nuclear protein 2

Epigenetics and Nuclear Signaling

TINF2