Full product name
TRIF Antibody
Code
BT-AP09200
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from TRIF at AA range: 663-712
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage
-20°C for one year
Background
TICAM1 (toll like receptor adaptor molecule 1) encodes an adaptor protein containing a Toll/interleukin-1 receptor(TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors(TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response.
Uniprot accession
Molecular weight
76422
Gene ID
Human: 148022; Mouse: 106759
Synonyms
TIR domain-containing adapter molecule 1 (TICAM-1) (Proline-rich, vinculin and TIR domain-containing protein B) (Putative NF-kappa-B-activating protein 502H) (Toll-interleukin-1 receptor domain-contai
Research area
Immunology
Target protein
TICAM-1
