Vinculin Antibody

BT-AP09532

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthetic Peptide of Vinculin

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.

1 mg/ml

PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

-20°C for one year

Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for VCL, but the biological validity of some variants has not been determined.

Human: P18206; Mouse: Q64727; Rat: P85972;

123799

Human: 7414; Mouse: 22330; Rat: 305679

VCL; Vinculin; Metavinculin

Signal Transduction; Cardiovascular

VCL