ZnT-8 Antibody

BT-AP09752

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

The antiserum was produced against synthesized peptide derived from human SLC30A8. AA range:171-220

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

Zinc transporter 8 encoded by SLC30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. SLC30A8 is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.

Human: Q8IWU4; Mouse: Q8BGG0;

40729

Human: 169026

SLC30A8; ZNT8; Zinc transporter 8; ZnT-8; Solute carrier family 30 member 8

Signal Transduction; Metabolism

SLC30A8