Full product name
alpha-Smooth Muscle Actin Antibody
Code
BT-AP09774
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
Synthetic Peptide of α-Smooth Muscle Actin
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Formulation
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Storage
-20°C for one year
Background
The protein (actin, alpha 2, smooth muscle, aorta) encoded by ACTA2 belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in ACTA2 cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Uniprot accession
Molecular weight
42009
Gene ID
Human: 59; Mouse: 11475; Rat: 81633
Synonyms
ACTA2; ACTSA; ACTVS; GIG46; Actin, aortic smooth muscle; Alpha-actin-2; Cell growth-inhibiting gene 46 protein
Research area
Signal Transduction
Target protein
ACTA2
