Tumor necrosis factor receptor superfamily member 8

BPE132

Sandwich

5*96T,96T,15*96T

6.91 pg/mL

23.44-1500 pg/mL

Serum, plasma, cell culture supernates

Human

2-8°C

3.5h

CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of lymphocytes and may also play an important role in human immunodeficiency virus replication. As a regulator of apoptosis, CD30 protein induces cell death or proliferation, depending on the cell type, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. CD30 protein expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs), and CD30 is also linked to leukocytes in patients with chronic inflammatory diseases, including lupus erythematosus, asthma, rheumatoid arthritis and atopic dermatitis (AD). Cancer Immunotherapy Immune Checkpoint Immunotherapy Targeted Therapy

63747

943

CD30;D1S166E

TNFRSF8

Cancer,Immunology

CD30