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Home > Product > ELISA Kit > Mouse Bile Salt Export Pump, ABCB11 ELISA Kit

Mouse Bile Salt Export Pump, ABCB11 ELISA Kit

Mouse Bile Salt Export Pump, ABCB11 ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 4.56ng/L

Detection range: 10-2000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Mouse

Product Summary

Size: 48T,96T

Sensitivity: 4.56ng/L

Detection range: 10-2000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Mouse

Product overview

Full product name

Bile salt export pump

Code

E1883Mo

Assay type

Sandwich

Size

48T,96T

Sensitivity

4.56ng/L

Detection range

10-2000ng/L

Sample type

Serum, plasma, cell culture supernates

Species

Mouse

Storage

2-8ºC

Assay time

1h 30m

Background

Catalyzes the transport of the major hydrophobic bile salts, such as taurine and glycine-conjugated cholic acid across the canalicular membrane of hepatocytes in an ATP-dependent manner, therefore participates to hepatic bile acids homeostasis and consequently to lipid homeostasis through regulation of biliary lipid secretion in a bile salts dependent manner (PubMed:14570929, PubMed:11172067, PubMed:23764895, PubMed:22619174, PubMed:19228692). Transports taurine-conjugated bile salts more rapidly than glycine-conjugated bile salts (By similarity). Also transports non-bile acid compounds, such as pravastatin and fexofenadine in an ATP-dependent manner and may be involved in their biliary excretion (By similarity).

UniProt accession

MASS(Da)

146,749

GeneID

27413

Synonyms

ABC1;ABC16;ABCB11;ATP-binding cassette sub-family B member 11;Bile salt export pump;Bs;Bsep;Lit;Lith1;PFI;PFIC2;PGY;Sister of P-glycoprotein;SPGP

Gene names

Abcb11

Research area

Signal Transduction

Target protein

ABCB11

Components

Components Quantity
Pre-coated ELISA plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E1883Mo are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
1200ng/L 2.321 2.339 2.277
2.358
600ng/L 1.437 1.435 1.373
1.432
300ng/L 0.776 0.734 0.672
0.692
150ng/L 0.405 0.467 0.405
0.528
75ng/L 0.244 0.256 0.194
0.269
0ng/L 0.057 0.062 0
0.068

Precision

We measured random samples of E1883Mo within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 168.78 9.74 5.77
Intra-Assay 2 18 570.5 17.23 3.02
Intra-Assay 3 18 321.46 18 5.6

Protocols

References

Customer reviews and Q&As

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  • Size

    Code

    Price

  • 48T

    E1883Mo

    $320.00

  • 96T

    E1883Mo

    $458.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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