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Home > Product > ELISA Kit > Human Anti-oxidized Low Density Lipoprotein Antibody, OLAB ELISA Kit

Human Anti-oxidized Low Density Lipoprotein Antibody, OLAB ELISA Kit

Human Anti-oxidized Low Density Lipoprotein Antibody, OLAB ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 0.5ng/ml

Detection range: 1-300ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product Summary

Size: 48T,96T

Sensitivity: 0.5ng/ml

Detection range: 1-300ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product overview

Full product name

Anti-Oxidized Low Density Lipoprotein Antibody

Code

E2295Hu

Assay type

Sandwich

Size

48T,96T

Sensitivity

0.5ng/ml

Detection range

1-300ng/ml

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria.

UniProt accession

MASS(Da)

30,959

GeneID

4973

Synonyms

CLEC8A;C-type lectin domain family 8 member A;hLOX-1;Lectin-like oxidized LDL receptor 1;Lectin-like oxLDL receptor 1;Lectin-type oxidized LDL receptor 1;LOX1;LOX-1;LOXIN;OLAb;Oxidized low-density lipoprotein receptor 1;Oxidized low-density lipoprotein receptor 1, soluble form];Ox-LDL receptor 1;SCARE1;SLOX1

Gene names

OLR1

Research area

Others

Target protein

OLAb

Components

Components Quantity
Pre-coated ELISA plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E2295Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
160ng/ml 2.087 2.096 2.051
2.104
80ng/ml 1.364 1.25 1.206
1.137
40ng/ml 0.827 0.844 0.8
0.862
20ng/ml 0.487 0.495 0.451
0.504
10ng/ml 0.175 0.197 0.153
0.22
0ng/ml 0.06 0.045 0
0.029

Precision

We measured random samples of E2295Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 44.53 2.45 5.49
Intra-Assay 2 18 128.59 4.76 3.7
Intra-Assay 3 18 31.53 2.31 7.34

Protocols

References

Customer reviews and Q&As

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  • Size

    Code

    Price

  • 48T

    E2295Hu

    $320.00

  • 96T

    E2295Hu

    $458.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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