Interleukin-3 receptor subunit alpha

E5521Hu

Sandwich

48T,96T

0.048ng/ml

0.1-40ng/ml

Serum, plasma, cell culture supernates

Human

2-8ºC

1h 30m

Interleukin 3 receptor, alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123), is a human gene. The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y.

43,330

3563

CD antigen CD123;CD123;hIL-3Ra;IL-3 receptor subunit alpha;IL3R;IL-3R subunit alpha;IL3RA;IL-3RA;IL-3R-alpha;IL3RAY;IL3RX;IL3RY;Interleukin-3 receptor subunit alpha;

IL3RA

Immunology; Signal Transduction

IL3RA