Protein JTB

E5985Hu

Sandwich

48T,96T

4.38ng/L

10-2000ng/L

Serum, plasma, cell culture supernates

Human

2-8ºC

1h 30m

Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity). Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential (By similarity).

16,358

10899

hJT;HJTB;HSPC222;JTB;Jumping translocation breakpoint protein;PAR;PAR protein;Prostate androgen-regulated protein;Protein JTB;

JTB

Others

JTB